six weeks in, fasting glucose fell from 112 to 98. appetite’s subtle though - eating normal portions if i’m not thinking about it. everyone talks about instant appetite suppression and i’m wondering if that’s just the loudest effect, not the first one. fasting insulin dropped too, so the drug’s working on something. my doc said keep going. real question: is appetite suppression the actual early sign, or just the most noticeable? if glucose is shifting but appetite isn’t, should i expect appetite suppression to catch up later? asking bc all the month-1 posts focus on “not hungry” and i’m tracking glucose instead. feels like a different marker but i can’t tell if it’s fine or if i’m missing something.
fasting glucose 112 to 98 at week 6 is a genuinely good signal. GLP-1 receptor agonism improves hepatic glucose output before appetite suppression is even perceptible for a lot of people, so what you’re seeing isn’t a failure of the drug, it’s a different mechanism running ahead of schedule. the “not hungry” posts are loud bc it’s the most subjective and easy to report. insulin dropping alongside glucose is the more meaningful pair to track anyway. appetite response varies a lot by dose and individual. your doc is right, keep going.
Your fasting insulin drop is what actually matters - glucose suppression alone would be temporary. appetite’s what everyone posts about; hepatic control is what you’re tracking.
“hepatic control is what you’re tracking” is right, but appetite suppression also functions as a dose-adequacy signal, not just a downstream effect everyone posts about. If it’s still minimal around weeks 10-12 with no titration, that’s worth raising with your endo as context for whether you’re at an effective dose yet, not necessarily as an alarm. My glucose moved well before hunger shifted too, maybe a 3-4 week gap at 2.5mg. I log both markers in CareClinic’s monthly summary specifically bc seeing the lag in one view kept me from conflating “appetite not suppressed yet” with “drug isn’t working” - which is a different and more important conclusion.