Third week on sertraline (Zoloft)

I have a panic/anxiety disorder and my doctor prescribed Zoloft. I started with 25 mg for a week and then increased to 50 mg. For the last three days, I felt fantastic—completely free of anxiety and thought I was past the initial side effects. However, last night and today, I’ve been experiencing waves of anxiety, pins and needles in my arms and legs, and nausea. I couldn’t sleep at all and am feeling really frustrated. Is it normal to have such a setback, and when can I expect more consistent relief from these symptoms?